transglutaminase

transglutaminase
An important extracellular enzyme that catalyses the formation of an amide bond between side-chain glutamine and side-chain lysine residues in proteins with the elimination of ammonia. The linkage is stable and plays an important role in many extracellular assembly processes.

Dictionary of molecular biology. 2004.

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  • Transglutaminase — Transglutaminases are a family of enzymes (EC 2.3.2.13) that catalyze the formation of a covalent bond between a free amine group (e.g., protein or peptide bound lysine) and the gamma carboxamid group of protein or peptide bound glutamine. Bonds… …   Wikipedia

  • Transglutaminase — La transglutaminase est une enzyme (EC 2.3.2.13) qui catalyse la formation de liaisons covalentes entre des groupements amines libres (ex. : lysines) et le groupement gamma carboxamide des glutamines. Les liaisons formées par la… …   Wikipédia en Français

  • Transglutaminase — Protein Glutamin γ Glutamyltransferase Bezeichner Externe IDs CAS Nummer:  …   Deutsch Wikipedia

  • transglutaminase — noun Any of a family of enzymes that catalyze the reaction of lysine and glutamine groups in proteins and have a function in blood coagulation …   Wiktionary

  • transglutaminase — A group of enzymes that catalyze the calcium dependent acyl transfer reaction in which the amide moiety of peptide bound glutaminyl residues serve as acyl donor; a specific t. covalently cross links fibrin molecul …   Medical dictionary

  • Keratinocyte transglutaminase — Transglutaminase 1 (K polypeptide epidermal type I, protein glutamine gamma glutamyltransferase), also known as TGM1, is a human gene.cite web | title = Entrez Gene: TGM1 transglutaminase 1 (K polypeptide epidermal type I, protein glutamine gamma …   Wikipedia

  • Anti-transglutaminase antibodies — AutoAbBox Autoantigen = transglutaminase SharedInfo = Yes CommentShared Answer Yes only if true SI Gene = SI Organ = SI Tissue = SI Cell = SI Also = SI Disease = SI Class = IgA, IgG SI IgGSubclass = SI HLA1 = DQ2.5 SI HLA2 = DQ8 SI HLA3 =… …   Wikipedia

  • Tissue transglutaminase — (abbreviated as TG2 or tTG) is an enzyme (EC number|2.3.2.13) of the transglutaminase family. Like other transglutaminases, it crosslinks proteins between an epsilon; amino group of a lysine residue and a gamma; carboxamide group of glutamine… …   Wikipedia

  • TGase — transglutaminase …   Medical dictionary

  • TGase — • transglutaminase …   Dictionary of medical acronyms & abbreviations

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